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    D4 response to treatment (Peritoneal Dialysis)


    D4 response to treatment (Peritoneal Dialysis) Empty D4 response to treatment (Peritoneal Dialysis)

    Post  *alexus on Thu 25 Jun 2009, 11:13 pm

    Balajadia/Zano response to treatment (Peritoneal Dialysis )

    Acceptability of Two-Liter Volume in Filipino Chronic Ambulatory Peritoneal dialysis (CAPD) Patients

    The study aims to determine if there is any significant difference in the symptoms of patients resulting from the use of the 1.5-liter versus the 2.0-liter CAPD bag in patients on regular CAPD. It is randomized clinical trial, which was done in a tertiary renal disease referral center. Patients were randomized to receive either1.5-liter or 2.0-liter fill volumes using a 1.5% dextrose solution, with the dialysate allowed to dwell for 2 hours. Patients were then asked to answer a questionnaire to determine if they experienced any discomfort during the dwell period. Symptom scored analysis was also done using a score of one point for every type of discomfort experienced by the patient and 0 if the symptom is absent. The number of patient each group who had no discomfort symptoms (Group A), discomfort symptoms scores > 0 but < (Group B), or > 5 discomfort symptoms (Group C), was determined.


    Fourteen patients (46.7%) in the 1.5-liter group and 11 patients (36.7%) in the 2.0-liter group experienced discomfort symptoms.

    Only three patients in each of the two-study groups (10.0% of both groups) experienced actual abdominal pain.

    The proportion of patients with difficulty of breathing, abdominal pain and difficulty in sitting were significantly higher among those who received 1.5-liter fluid as compared to those who received 2.0-liter fluid.

    Results showed that there was no significant difference in discomfort when patients used the1.5-liter or 2.0-liter volume. Symptom scored analysis also revealed that there were no significant differences between the symptom scores from the 1.5-liter group versus the 2.0-liter group.


    As the result of the study, Renal Physicians and Nurses should be confident of the tolerability of the Filipino patients to the 2.0-liter dialysate bag. Cost savings of about P4.740 per month using 3 exchanges of 2.0-liters compare to the current standard therapy of 4 exchanges of 1.5-liters could help the patient sustain their medical expenses, achieving the state of well being in low cost.

    Danguilan et al. NKTI proceedings 5: August 2003.

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